Matt Dillon

Eddie Megeffin (segment 'Return to Kansas City')

Kyra Sedgwick

Arlene Megeffin (segment 'Return to Kansas City')

Ray Liotta

Martin (segment 'A Domestic Dilemma')

Andie MacDowell

Emily (segment 'A Domestic Dilemma')

Scott Glenn

Henry (segment 'Mara')

Juliette Binoche

Mara (segment 'Mara')

Jerry Stiller

Irving (segment 'Return to Kansas City')

Kevin Rooney

Vince (segment 'Return to Kansas City')

Michael Russo

Boxing Opponent (segment 'Return to Kansas City')

Joe Santarpia

Referee (segment 'Return to Kansas City')

Jared Harris

Joey Patrick (segment 'Return to Kansas City')

Jane Krakowski

Melba (segment 'Return to Kansas City')

Ashley Affrunti

Baby (segment 'Return to Kansas City')

Brittany Affrunti

Baby (segment 'Return to Kansas City')

Bill Corsair

Radio Announcer (voice) (segment 'Return to Kansas City')